Mari Katayama has won the $63,000 inaugural Mori Art Award.
The Japanese artist, who had both her legs amputated aged nine, uses photography and hand-sewn fabric to make her body into a living sculpture.
She told the Japan Times: "I want to tell everyone who is still moving forward, even quietly and invisibly, that effort does bear fruit. To me, this Grand Prix is not only an award — it is the opportunity to carry that message further."
The prize was set up by the Mori Contemporary Art Foundation to "support mid-career artists set to become the next leading figures in contemporary art" and also includes the opportunity of an exhibition at the Mori Art Museum in Tokyo.
Katayama was chosen as the winner by an international jury including the museum's director, Mami Kataoka, the former director of New York's Museum of Modern Art, Glenn Lowry, and Frances Morris who was formerly Director at London's Tate Modern.